Management of open fractures post debridement with standard empirical antibiotics and culture specific antibiotics: A randomized control study
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 4, Pages 3749-3756
AbstractThe goals of open fracture management include preventing infection, achieving bone union, and restoring function. Current treatment strategies for the care of open fracture wounds are constantly being updated. Important principles for management include rational antibiotic usage, anti- tetanus prophylaxis, appropriate timing of initial surgical intervention, wound irrigation, antibiotic delivery methods, and type of wound closure and adjunctive therapies to aid fracture union. All patients underwent trauma assessment and appropriate treatment in the emergency department, the wounds were inspected for the size and extent of wound, both soft tissue and bone status was assessed and the amount of contamination was noted. The most common organism isolated from post-operative infected cases was Staphylococcus aureus (53%) a gram-positive cocci and the next common was Pseudomonas aeruginosa (20%) a gram negative bacilli and other gram negative bacteria, Escherichia coli and Klebsiella pneumoniae.
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