A PROSPECTIVE STUDY OF EFFECT OF GLYCAEMIC STATUS ON PULMONARY FUNCTION TEST IN TYPE 2 DIABETES MELLITUS
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 3, Pages 1283-1287
Abstract
Introduction: Diabetes mellitus as we all know is a systemic disorder which affects many organs by causing pathological changes in them. It is considered as a leading cause of increasing morbidity and deaths in today’s world. Many studies suggested that lung is a target organ in DM and that glycaemic exposure is a strong determinant of reduced pulmonary function in DM patients theoretically morbidity, several pathological changes may affect the lungs in patients with DM.Materials and methods: This prospective study was conducted over a period of one year from January 2021 to December 2021 (1 year). 100 type-2 diabetic patients who were not on insulin visiting Shaheed Nirmal Mahato Medical College (SNMMCH), Dhanbad as in-patients & out-patients were included. The sample size was taken based on the convenience of the study. 100 healthy controls who’s fasting blood sugar (FBS) and postprandial blood sugar (PPBS) were in normal limits from administrative office of Shaheed Nirmal Mahato Medical College (SNMMCH), Dhanbad, and other volunteers constituted the control group. The informed consent of the patient / guardian was obtained.
Results: FBS among cases and controls were compared which shows a mean FBS value of 207.8 mg / dl in diabetic group as compared to a mean value of 97.42 mg/dl in controls with P value of 0.001 which is highly significant. Post prandial blood sugars showed highly significant difference among both groups with mean of 254.41 among diabetic group and 126.65 among controls.
Conclusion: Type 2 diabetes mellitus is associated with restrictive pattern of respiratory abnormality. As the duration of diabetes increases the restrictive profile was more prominent. There was inverse relation between glycaemic status and spirometric indices FEV1 and FVC. Thus, an intensive glycaemic management may reduce the risk of death through an improved ventilator function which is independent of the other beneficial effects.
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