A retrospective cohort study to assess the levels of IL-6 in COVID-19 infected patients and to evaluate its association with the severity of the disease in Jodhpur, Rajasthan
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 4, Pages 3866-3872
Abstract
Background: The SARS-CoV-2 virus replicates rapidly, triggering a storm characterized by increased levels of cytokines such as IL-6. Such an inflammatory response causes inflammation of the respiratory system and other bodily systems, with subsequent occurrence of ARDS or respiratory failure. The estimation of IL-6 levels could be an important tool to assess disease severity in COVID-19 patients.Methodology: A retrospective cohort study was conducted on 45 patients in Department of Medicine, MDM Hospital, Dr. S.N Medical College, Jodhpur, Rajasthan. A predesigned and pre-structure Performa was used.
Conclusion: IL-6 is an adequate predictor of severe disease in patients infected with the COVID-19 virus. The finding of current study guide clinicians and healthcare providers in identifying potentially severe or critical patients with COVID-19.
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