Correlation between fasting and postprandial triglyceride levels and carotid intima-media thickness in type 2 diabetes patients at tertiary care hospital in western Rajasthan
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 4, Pages 3873-3881
AbstractBackground: Globally, diabetes is one of the most common non-communicable diseases leading to mortality and morbidity in many developed countries. Insulin resistance and obesity both combine to cause dyslipidemia and hyperglycemia. Postprandial triglycerides may have a greater role in the atherosclerotic process than fasting triglycerides. Patients with early atherosclerotic changes are generally asymptomatic. Only when the vascular occlusion reaches a significant percentage do they become symptomatic. Assessing carotid intimal thickness using carotid Doppler has been shown as a non-invasive and quantitative method to detect these early changes
Methodology: A cross sectional study was conducted in S.N.M. College, Jodhpur on 133 patients. Complete physical examination of each participant were done. Bilateral images of the common carotid arteries, internal carotid artery and carotid bulb is obtained by a lateral view by a single experienced radiologist who has expertise in cross sectional imaging. The gap between the media-adventitia interface and lumen-intima interface is the IMT.
Conclusion: Fasting and postprandial triglyceride level both correlate significantly with carotid intima media thickness. But the correlation of postprandial triglyceride level with CIMT is better than that of fasting triglyceride level.
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