Study of correlation of presence of microalbuminuria to target organ damage in essential hypertension cases at SKMCH, Muzaffarpur, Bihar
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 6, Pages 1322-1327
AbstractBackground: It has long been known that a critical level of urine albumin excretion is a reliable indicator of cardiovascular events in hypertension patients. Except for cardiovascular events, very few studies have been done to date showing a relationship between microalbuminuria and target organ damage in patients with essential hypertension. In individuals with essential hypertension, we looked at the frequency of microalbuminuria and how it related to organ damage.
Methods: 120 patients with essential hypertension in total were investigated. Analysis was done on the prevalence of urine albumin excretion and its relationship to stroke, retinopathy, and left ventricular hypertrophy as target organ damage. Turbidimetry was used to measure the excretion of urinary albumin, and the urine albumin to creatinine ratio was used to measure the presence of microalbuminuria.
Results: In 57.7% of the patients, microalbuminuria was discovered to be present. In 62.5% (75 patients) of the cases, the target organ was damaged, and in 78.66% of these cases, microalbuminuria was also present (p 0.05). Among these, patients with longer durations and more severe forms of hypertension, elevated body mass indexes, and dyslipidemia showed higher prevalence.
Conclusions: A crucial diagnostic for determining the extent of target organ damage in hypertensive individuals is the examination of microalbuminuria. Reduced risk of microalbuminuria results with optimal hypertension management, weight control, and maintenance of normal lipid levels.
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