CURRENT SCENARIO AND FUTURE ORCHESTRATIONS IN THE BATTLE AGAINST DYSLIPIDEMIA: REVIEW ON NOVEL HYPOLIPIDEMIC DRUGS
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 7, Pages 162-184
AbstractCholesterol is an essential constituent of the cell membrane. It coordinates carbohydrate, major ions, and bone homeostasis respectively.  Cholesterol is the progenitor for all glucocorticoids, mineralocorticoids, sex hormones, steroids, and cholecalciferol. Cholesterol is transported into the blood via spherical macromolecules like chylomicrons, HDL, LDL, and VLDL.  These properties make it an essential biomolecule for most physiological mechanisms. Triglycerides performing a key role in providing energy to cells.  In excess amounts, these biomolecules are not good for health and produce hyperlipidemia.  Hyperlipidemia is responsible for many long-term side effects in the body. Hyperlipidemia increases the risk of formation of plaques, which promotes the risk of heart attack and stroke in persons with atherosclerosis and coronary heart diseases.  Statins are the evidence-based treatment option for hyperlipidemia according to published guidelines.
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