STUDY OF ROLE OF PLATELET COUNT AND MEAN PLATELET VOLUME IN EVALUATING THE DISEASE SEVERITY IN COVID 19 INFECTION-OUR EXPERIENCE AT TERITARY CARE HOSPITAL
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 7, Pages 185-192
AbstractINTRODUCTION: Patients Infected with CORONA VIRUS- 2019 (COVID-19) showed changes in their platelet counts and Mean platelet volume (MPV). The present study was aimed to observe any association between lowered platelet counts with mean platelet volume (MPV) from the corana positive individuals.
METHODS: It is a prospective study from 1-8-2020 to 30-9-2020 .Patients who presented with complaints of Fever, sore throat, body pains, cough, breathlessness, diarrhoea were evaluated at the triage area of the Hospital. Throat swab was taken and RT-PCR was done and only 200 confirmed cases were included in the study. Patient blood samples were collected and processed in SYSMAX 5 -part Haematology analyser in the Hospital Central Laboratory. The patients CBP, Platelet count and MPV were tabulated.
RESULTS: Out of 200 COVID-19 confirmed cases, the numbers of males were 145 (72.5%) and females 55 (27.5%). Most of the patients belonged to age group 50 years (25.5%), 60yrs age group (21%). The Maximum age in our study group was 80 years, minimum age was 19 years and mean age was 50 years. In our study it was noticed that Severe thrombocytopenia was seen in one patient with platelet count 38,000/μL,(0.5%), Moderate thrombocytopenia was seen in two patients(1%) and mild thrombocytopenia was seen in 12 (6%) cases. In our study only fifteen cases (7.5%) showed thrombocytopenia. The MPV for all fifteen cases were studied and MPV was in Range of 9.6- 11.8 fl.
CONCLUSION: Low platelet count and high MPV are associated with disease severity. Platelet count is one of easy cheap method for the assessing the disease severity along with other parameters
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