OXIDATIVE STRESS AND PSYCHOLOGICAL STRESS AMONG SUBJECTS WITH RECURRENT PREGNANCY LOSS
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 7, Pages 539-547
AbstractRecurrent pregnancy loss (RPL), known popularly as recurrent miscarriage, is a clinical condition of two or more failed pregnancies, affecting 12-15% of total pregnancies. Besides genetic and anatomical abnormalities, stress and anxiety impart a vital role in repeated abortions. The Perceived Stress Scale, an extensively used psychological tool for assessing the perception of stress in an individual, was taken for evaluating the role of psychological stress among subjects with RPL. The oxidative stress marker, malondialdehyde (MDA) and several other clinical parameters were also analyzed among 150 women with RPL and 110 healthy women with one or two children. The study concluded that RPL individuals are shown to have higher rates of oxidative and psychological stress with elevated MDA concentration and PSS score respectively.
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