Document Type : Research Article
Introduction: The effective intrapartum analgesia greatly minimizes pain, stress, and anxiety which cause release of stress hormones as well as beta-endorphins. This this present study is followed to evaluate the effect of intrathecal labour analgesia on the progress of labour was compared between fentanyl 25μg alone and fentanyl 20μg plus bupivacaine 2.5mg. Materials and Methodology: Patients in the group SA (n = 33) were administered with an intrathecal injection of 0.5% hyperbaric bupivacaine 2.5 mg (0.5 mL) and fentanyl 25 µg (0.5 mL), volume made to 1.5 mL with normal saline. And the matching group C (n = 33) who refused to give consent for neuraxial analgesia. The two groups were evaluated with regards to the progress of labour, maternal hemodynamic variations, foetal heart rate, and neonatal outcome during labour in parturient undergoing normal vaginal delivery. Results: Parturient in group SA has gained excellent pain relief throughout their labour and VAS score remained less than 4 till delivery as compared to group C, in which VAS score was more than 7 at all time. There were no observed significant changes in FHR when compared to the baseline in both the groups and none had observed with the interventions of foetal compromise. The mode of delivery in all parturient in the study group was mostly vaginal delivery without any instrumental delivery. The parturient who required caesarean section due to other indication were excluded from the study. Conclusion: A a single dose of intrathecal fentanyl 25 μg and bupivacaine 25 mg which were given in the active phase of first stage of labour had rapid onset with satisfactory pain relief and minimal motor block, which completely regressed at the time of second stage of labour.