European Journal of Molecular & Clinical Medicine

Abstract

Background: Optic neuritis causes substantial visual impairment and potential long-term visual defects in addition to serving as an important prognostic indicator for future development of demyelinating diseases such as multiple sclerosis. So, an ophthalmologist has a very significant role to aid in prevention of full blown MS. Fortunately, in most cases, optic neuritis recovers either spontaneously or with treatment. Recovery can be partial or absolute, depending largely upon severity and co-existing conditions.
Aim: To study the clinical profile and visual outcomes in patients with optic neuritis.
Material and methods:A prospective observational study was conducted in the Department of ophthalmology, MMIMSR Mullana, Ambala for which approval was obtained from the ethical committee of the institution. Patients of ON were included in the study after obtaining informed consent. Total 60 cases were studied. Analysis was done using SPSS and Pohnpei software.
Results:The mean age of presentation was 39.3667 ± 14.03563. ranging from 16 to 75 years.Out of 60 patients, retrobulbar neuritis was diagnosed in 34 [56.7%] whereas papillitis was diagnosed in 26[43.3%].After ONTT all patients showed improvement in vision. This improvement in vision is statistically significant.
Conclusion:The results revealed that the prevalence of papillitis and RBN were almost equal. Patients with RBN responded quickly to ONTT regimen while papillitis recovered late. VA improvement after ONTT was statistically significant. Colour vision and contrast also improved. Our study showed that ONTT regimen has a benefit in optic neuritis with fast visual recovery.