• Register
  • Login

European Journal of Molecular & Clinical Medicine

  1. Home
  2. Evaluation of Intravascular Volume and Inotrope Status at ICU Admission as Predictors of Acute Kidney Injury

Current Issue

By Issue

By Author

By Subject

Author Index

Keyword Index

About Journal

Aims and Scope

Editorial Board

Publication Ethics

Indexing and Abstracting

Related Links

FAQ

Peer Review Process

Journal Metrics

News

Evaluation of Intravascular Volume and Inotrope Status at ICU Admission as Predictors of Acute Kidney Injury

    Author

    • Mayurdhwaja Rath, LN Yaddanapudi, Vikas Saini

    India

,

Document Type : Research Article

  • Article Information
  • Download
  • Export Citation
  • Statistics
  • Share

Abstract

Introduction: Acute kidney injury is a leading cause of morbidity and mortality in critically ill patients. We hypothesized that inadequate fluid resuscitation and high vasopressor use before admission to the ICU can predict the occurrence of AKI in critically ill patients.
Objectives: The aim of this study was to determine the ability of IVC collapsibility index (measure of intravascular volume inadequacy) and the vasopressor therapy at ICU admission to predict the development of AKI.
Material and Methods: We prospectively recruited 103 patients in our 12 bed ICU from October 2017 to June 2018, after written informed consent from the next-of-kin, excluding Patients with CKD or transplanted kidneys and in whom IVC couldn’t be measured. Demographic data, baseline vital signs, investigations, ongoing inotrope dosage and duration were noted. Maximum and minimum IVC diameters were measured by 3.5 MHz ultrasound probe in M-mode in the transthoracic subxiphoid view and IVC collapsibility index was calculated. Daily urine output and serum creatinine values were collected up to 7 days. The AKI was diagnosed by KDIGO criteria. Multivariate logistic regression analysis was done with AKI as independent variable and age, gender, APACHE II score on admission, vasopressor use and number of vasopressor at admission and the collapsibility index as possible predictors.
Results: 78% of the patients developed AKI by the 7th day of ICU stay. Only APACHE II score at admission was significantly associated with AKI.
Discussion: The IVC collapsibility index and vasopressor use were not predictive of AKI. Vasopressor use in our sample was only 22%. It is possible that collapsibility index at admission to ICU is not a good indicator of pre-ICU volume status. Future studies should concentrate on volume status estimation and resuscitation in the wards before ICU transfer.

  • XML
  • PDF 398.54 K
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
    • Article View: 33
    • PDF Download: 92
European Journal of Molecular & Clinical Medicine
Volume 9, Issue 7
September 2022
Page 2339-2350
Files
  • XML
  • PDF 398.54 K
Share
Export Citation
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
Statistics
  • Article View: 33
  • PDF Download: 92

APA

Vikas Saini, M. R. L. Y. (2022). Evaluation of Intravascular Volume and Inotrope Status at ICU Admission as Predictors of Acute Kidney Injury. European Journal of Molecular & Clinical Medicine, 9(7), 2339-2350.

MLA

Mayurdhwaja Rath, LN Yaddanapudi, Vikas Saini. "Evaluation of Intravascular Volume and Inotrope Status at ICU Admission as Predictors of Acute Kidney Injury". European Journal of Molecular & Clinical Medicine, 9, 7, 2022, 2339-2350.

HARVARD

Vikas Saini, M. R. L. Y. (2022). 'Evaluation of Intravascular Volume and Inotrope Status at ICU Admission as Predictors of Acute Kidney Injury', European Journal of Molecular & Clinical Medicine, 9(7), pp. 2339-2350.

VANCOUVER

Vikas Saini, M. R. L. Y. Evaluation of Intravascular Volume and Inotrope Status at ICU Admission as Predictors of Acute Kidney Injury. European Journal of Molecular & Clinical Medicine, 2022; 9(7): 2339-2350.

  • Home
  • About Journal
  • Editorial Board
  • Submit Manuscript
  • Contact Us
  • Glossary
  • Sitemap

News

 

For Special Issue Proposal : editor.ejmcm21@gmail.com

Newsletter Subscription

Subscribe to the journal newsletter and receive the latest news and updates

© Journal Management System. Powered by ejournalplus