Document Type : Research Article
Abstract
INTRODUCTION: Rheumatoid Arthritis (RA) is a chronic systemic inflammatory disorder of unknown aetiology that may affect many tissues and organs In the previous years, various authors have studied the association between disease activity of RA and these haematological parameters separately. The current study intended to find out the association of DAS 28-score of RA with platelet count, MPV and Hb level so that an assessment of disease activity of RA can be done by these haematological parameters in addition to conventional serological markers so that a better management of the patients of RA can be done.
MATERIAL AND METHODS; patients of rheumatiod arthritis attending rheumatology opd were randomly selected and detail history and examination done. Lab investigation like CBC, ESR, CRP, S.ferritin done.
RESULT: rheumatiod arthritis was more common in female with rheumatiod factor positivity in 80% and prevelance of anemia was 73.3%. Anemia is very well correlated with rheumatoid factor positivity, disease activity (das 28 score),duration of disease and ESR.
CONCLUSION: The anemia is the one of the indicator of disease severity and anemia incidence is more in our Population. It was also observed that thrombocytosis and eosinophilia also the indicators of disease severity which positively correlated with DAS 28 score
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