European Journal of Molecular & Clinical Medicine

Abstract

BACKGROUND
More than 95% of people with diabetes have type 2 diabetes. Apart from the micro and macrovascular complications people with diabetes especially patients with long standing diabetes have new complication with degenerative muscle disease called as sarcopenia. The prevalence of sarcopenia is more in diabetics and sarcopenia itself is a risk factor for diabetes mellitus. It’s a controversial bidirectional association.
OBJECTIVES / AIMS
To study the clinical profiles and association of sarcopenia and non-sarcopenic patients with T2DM
MATERIALS AND METHODS
It is a cross sectional observational study done in RIMS hospital, Raichur. All the patients aged above 18 years and have been diagnosed with type II diabetes for the last 1 year had been included in the study. Patients were subjected to anthropometric measurements and we measured hand grip strength (HGS) using a medical handgrip dynamometer. Based on the observation we categorised them to sarcopenic group and non sarcopenic group. The clinical profile of both groups were then compared and statistically analysed.
RESULTS
A total of 100 patients were included in the study who met inclusion and exclusion criteria. Among them, 30 patients had sarcopenia. Mean age of presentation was 66.3 Years. Males were more in sarcopenic group. The mean BMI in sarcopenic patients group was 21.3 which were far less compared to non sarcopenic patients group (28.5).
CONCLUSION
Sarcopenia is common in adults over the age of 70 years and in males. BMI is a strong predictor of skeletal muscle mass. There is significant association with type 2 diabetes mellitus and sarcopenia especially when the patients are having long standing diabetes and associated complications.