European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Fluid resuscitation is essential to treat hypovolemia and restore organ perfusion. Respiratory variation in arterial pulse pressure is a reliable predictor of fluid responsiveness in mechanically ventilated patients with circulatory failure.  Respiratory variation in arterial pulse pressure is a reliable predictor of fluid responsiveness in mechanically ventilated patients. Respiratory variations in Pulse Oximetry Plethysmographic waveform peaks also correlate with pulse pressure variability in similar settings.
Aim and objective: The purpose of this study was to assess the relationship between respiratory variations in pulse oximetry plethysmographic waveform amplitude and arterial pulse pressure in ICU patients of a tertiary care hospital in south India.
Methodology: A hospital-based prospective observational study was done at MDICU Department of Anaesthesiology, College Hospital, Trivandrum, s tertiary care hospital for a period of 1 year and 6 months. A total of 77 participants were included in this study. 
Result: The correlation between Pulse Pressure and Pulse Oximetry Plethysmography was statistically not significant.
Conclusion: The Large variability of ∆POP and poor agreement between ∆PP and ∆POP limit the calculation of POP as a potential non-invasive tool for fluid responsiveness in ICU patients. The same analysis should be done with a non-processed plethysmographic signal before ruling out ∆POP as a surrogate of ∆PP.