European Journal of Molecular & Clinical Medicine

Abstract

The current study aims at bacterial and fungal etiology of Cholesteatoma in patients attending tertiary care hospital. Cholesteatoma is an abnormal, noncancerous skin growth that can develop in the middle section of ear, behind the eardrum. It is a complication of chronic suppurative otitis media. With the informed consent, 70 patients with Cholesteatoma were included; 42 (60%) were male and 28 (40%) were female, and the mean age was 11-50 years. Materials and methods- Cholesteatoma sac and 2 preoperative swabs were collected from ENT OPD patients complaining of earache and discharge. Results- Out of 70 patients, 28 were sterile samples, 40 (41.7%) showed aerobic bacteria and 2 (1.3%) had fungal etiologies. Conclusion- Gram negative pathogen forms most aural swabs and Cholesteatoma sacs. Pseudomonas aeruginosa was the predominant isolate 18(25.7%), followed by Staphylococcus aureus
11(15.7%) and their antimicrobial susceptibility testing was done. Though the treatment of Cholesteatoma is surgery but to avoid recurrence, the use of proper antibiotics by knowing the antibiogram will lead to a decrease in the prevalence of microbial growth and recurrence of Cholesteatoma.