European Journal of Molecular & Clinical Medicine

Abstract

Background and Aims: Low blood gas solubility coefficients of desflurane and sevoflurane enable a quick recovery from anaesthesia. Desflurane, meanwhile, has a strong smell and might irritate the airways. While employing the ProSealTM laryngeal mask airway, we examined the effects of desflurane and sevoflurane on recuperation and the occurrence of adverse airway reactions in patients who were breathing on their own (LMA). Methods: In 94 adult patients who received hysteroscopic operations, sevoflurane (S) or desflurane (D) groups were created. Fentanyl 1 g/kg and midazolam 0.03 mg/kg were used as premedicators on the subjects. Adverse airway reactions, such as coughing, hiccups, laryngospasm, and breath holding, were observed after propofol 2.0-2.5 mg/kg was used to induce anaesthesia and a ProSealTM LMA was inserted. Time to awakening, verbal command response, orientation, the capacity to sit with support, and the Aldrete score for the recovery area were all noted during the post-operative interval. Results: Three patients in group S (6.4%) and six patients (13.3%) in Group D had adverse airway events. The mean time to eye opening (Group S-10.75 ± 7.54 min, Group D-4.94 ± 1.74 min), obeying verbal commands (Group S-13.13 ± 8.75 min, Group D-6.55 ± 1.75 min), orientation (Group S-15.42 ± 8.46 min, Group D-6.23 ± 2.4 min) and to sit with support (Group S-36.09 ± 12.68 min, Group D-14.35 ± 3.75 min) were found to be lesser with desflurane than with sevoflurane (P < 0.001). The mean time to recovery was delayed in Group S-46.00 ± 12.86 min compared to Group D-26.44 ± 5.33 min (P < 0.001). Conclusion: Desflurane, when combined with propofol and fentanyl while spontaneous breathing with a Pro^SealTM LMA, exhibits faster awakening qualities than sevoflurane without a rise in adverse airway outcomes.