Abstract

Depending on the etiology of diabetes mellitus, factors contributing to hyperglycemia may include reduced insulin secretion, decreased glucose utilization, and increased glucose production. The metabolic dysregulation associated with diabetes mellitus causes secondary pathophysiologic changes in multiple organ systems. Diabetes mellitus is the leading cause of end-stage renal disease (ESRD), non-traumatic lower extremity amputation and adult blindness. The patients of type 2 diabetes mellitus without clinical evidence of coronary artery disease attending diabetic clinic, cardiology and medicine OPD, at medical college and hospital were enrolled in the present study. The average glycosylated hemoglobin (HbA lC) was 7.92, 7.78, 8.71 and 10.2 for the duration of diabetes equal to or less than 5 yrs, 6 to 10 yrs, 11 to 15 yrs and 16 to 20 yrs respectively. This shows that all patients had poor g1ycaemic control.