Predictors Of Survival After Curative Resection of Colorectal Carcinoma
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 6, Pages 2328-2337
AbstractAim: The aim of the present study was to evaluate the predicting factors affecting the survival after curative resections in carcinoma of Colon and Rectum.
Methods: The Gujarat cancer Research Institute is well suited for studying the natural history of carcinoma of the colon and rectum because comprehensive cancer unit records are available and accessible. This includes the diagnoses made among outpatients or emergency room visits, as well as diagnoses recorded among hospital inpatients. Using this system, we studied prospectively all 133 patients with carcinoma of the colon or rectum newly diagnosed between August 1, 2014 and July31, 2015; the cases were confirmed either histologically or radiologically followed by histology e.g., in obstruction.
Results: Out of 133, 60% (n=80) of the patients were in the age group of <60 years, 31.5% (n=42) in 60-70 years age group and 8.5% (n=11) in 70+ years age group. The youngest and oldest patient was 16 years and 84 years old respectively. Emergency symptoms like intestinal obstruction and fistula were presenting symptoms in 18.80% (n=26) and 0.70% (n=1). After radiological investigations, mass lesions were noted in various parts of colon (cecum, ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon and sigmoid colon) in 50% (n=67) of the patients. In 6% (n=8) patients’ lesions were noted in rectosigmoid while in 44% (n=58) it was in rectum.
Conclusion: There are multiple factors that can predict the survival – cure, recurrence free survival and overall survival at 2 years after curative resection in colorectal carcinoma. Keywords: Rectal, Colon, Carcinoma, Recurrence, Prognosis
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