European Journal of Molecular & Clinical Medicine

Abstract

Background: Allergic Rhinitis (AR), a not-unusual health problem, imposes a large problem on
public health. New proof shows a possible link between AR and vitamin D deficiency. Aim And
Objective: This study was done to determine whether serum Vitamin D levels are altered in AR
as compared to healthy controls.Materials and Methods: A cross-sectional study was performed
on 100 adults aged 20–50 (50 clinically diagnosed with AR and 50 age and sex-matched
controls). They were evaluated clinically and by determining serum levels of 25-
hydroxyvitamin D [25(OH) D]. Results: The most common symptom was paroxysmal
sneezing (82%). The mean and standard deviation concentration of serum 25(OH) D was 16.95 ±
3.77 ng/ml in patients and 24.25 ± 6.24 ng/ml in controls. This study demonstrated a statistically
significant Vitamin D deficiency (defined as serum 25(OH) D, ≤ 20 ng/ml) among the
patients with AR as compared to the healthy control (P-0.001).