European Journal of Molecular & Clinical Medicine

Abstract

Introduction:  Neoplasms of the urinary tract are commonly encountered in clinical practice and important from clinical and pathological perspectives as they have various histological patterns with prognostic implications.
Aim: The aim of this study was to observe the spectrum of lesions among various organs of the urinary tract and categorize them into benign and malignant based on histopathological findings.
Materials and methods:  This is a hospital based five-year retrospective study of urinary tract specimens received in the department of Pathology.
 Results: A total of 90 cases were studied, 87 cases were malignant, and 3 cases were benign. Among the malignant cases, most common were Clear Cell type of Renal Cell Carcinoma (RCC) in kidney, low grade urothelial carcinoma of the ureter/Renal pelvis and non-invasive low grade urothelial carcinoma in bladder.
Conclusion: Most of the lesions in the urinary tract had a male predominance with most patients being in the 6^th and 7^th decades. In kidney Clear Cell Renal Cell Carcinoma predominated, in bladder Non-invasive Papillary Urothelial Carcinoma was the commonest 9lesion and in renal pelvis /ureter Low grade urothelial carcinoma was the commonest.  Histopathological examination provides a confirmatory diagnosis which helps in the management and in assessing the prognosis of these lesions based on invasion into muscle, capsule, and adjacent tissues.