Study of symptoms following COVID-19 vaccination in Western Punjab
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 7, Pages 3279-3289
Abstract
Various types of COVID-19 vaccines with a variety of mechanisms of action have been developed recently in various countries throughout the world. At this stage only little is known about the post-vaccination experience beyond the clinical trials and very less information of vaccination side effect profile is known from real world scenario. Education of the general public regarding usual and expected post-vaccination symptoms will help in reducing reluctance for vaccination and improve willingness to get vaccinated.Aim
To assess the immediate response to the first dose of COVID-19 vaccine.
To study the spectrum of post-vaccination symptom profile for individual vaccines.
Methods
We conducted a cross-sectional survey which included questions particularly related to the immediate vaccine side effects from a North Indian population. Priority in India was given to healthcare workers, people above 50 years and those with co-morbidities below 50 years as it was rolled all across India on January 16th 2021. The survey was sent to all relevant participants who received COVID-19 vaccine till 5th March 2022.
Multiple choice question formats was used for extracting information from the participants.
Results
Approximately 500 people responded to the survey over a period up to 5th March 2022. Local pain at injection site was the most common symptom noted, followed by myalgia and tiredness. 80.3% people reported symptoms within the first 12 hours after receiving vaccination. In about 32.1% of people the symptoms persisted for 12 hours, 25.1 % for 13-24 hours 31% for 24-48 hours, 6.7% for 48-96 hours & in 5.1 % stayed for more than 96 hours.
Conclusions
70.6% of those who completed the survey reported short-lived post-vaccination symptoms. Local pain at injection site, fever, tiredness and myalgias were most commonly reported. Previous 2nd and 3rd trials of these vaccines too had revealed findings consistent with the present findings, suggesting an immune response commonly associated with vaccines
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