Abstract

Background: Oral submucous fibrosis (OSMF) is an oral precancerous condition characterized by inflammation and progressive fibrosis of the submucosal tissues resulting in marked rigidity and trismus. OSMF is still challenging for clinicians due to elusive pathogenesis and less well-defined classification systems.However current treatment strategy with oral lycopene andintralesional injection of  kennacort and hyaluronidase  is effective to some extent .
Methods: A total of 30 patients diagnosed with OSMF were treated in SMGS hospital, GMC jammu for a span of 9 months. They were treated with oral lycopene and intralesional injection of kennacort and hyaluronidase weekly for 6 weeks.
Results: There was significant improvement in opening of mouth and definite reduction in burning sensation, painful ulceration and blanching of buccal mucosa.
Conclusion: Management of OSMF includes counseling of patients along with oral lycopene with intradermal injection of kennacort with hyaluronidase, is highly effacious and cost effective in improving the mouth opening and recing other symptoms in patients with OSMF, whereas advanced stages should be treated surgically.