European Journal of Molecular & Clinical Medicine

Abstract

Background & Method: The aim of this study is to study the effect of Intravenous Dexmedetomidine in prevention of intra-operative shivering in the patients undergoing lower abdominal surgeries under spinal anesthesia.
Result: The mean sedation score in control group was 1.32 ± 0.47, while in study group it was 4.44 ± 0.61.  The difference was found to be statistically significant (P<0.05), with a higher sedation score in study group in comparison to control group. Statistically significant proportional difference was seen between control and study group for Grade 2, 3 and 4 (P < 0.05), with a higher proportion of patients in control group in comparison to study group.
Conclusion: Patients were randomly allocated in to two groups of 50 each, dexmedetomidine group and control group. Just after intrathecal injection drug were infused intravenously. Dexmedetomidine group was given an iv loading dose of dexmedetomidine 1mcg /kg administered over a 10 minute period followed by an infusion of 0.5mcg /kg body weight. The infusion was stopped at the end of the surgery. Control group were given normal saline slowly. Drug dexmedetomidine is effective in preventing shivering following spinal anesthesia The incidence of shivering in patients under spinal anesthesia after dexmedetomidine is 2% and in control group is 62 %.