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Histopathological Study of Gastrointestinal Stromal Tumors

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    • Maulik kumar P. Vora, Abhishek Raval, Manan Jadav, Ritesh Gohil, Karansinh F. Vala
,

Document Type : Research Article

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Abstract

Background: Gatrointestinal stromal tumor (GIST), now the most common mesenchymal tumor of the gastrointestinal tract(GIT), has been frequently studied.
Objectives: Our aim was to study histopathology, demographic profile, histopathological grading, IHC property and behavior of  Gastro intestinal stromal tumor(GIST)
Material & Methods: Retrospectively 50 cases were selected& studied from the department of histopathology of tertiary care hospital,  Ahmedabad, India during  june 2010 to june 2013
Results: 50 cases were studied in our study. Most common site was stomach(40%)followed by jejunum(18%), rectum(16%)& ileum(12%). Most common age group was 51-60 years. Most common presenting symptoms  was abdominal pain (70%)  Seventy  percent of  Gastrointestinal stromal tumor were positive for CD 117(KIT). Histologically majority of them had a pure spindle cell morphology. Eight patients (21%)  had  recurrent /residual  mass of presentation.
Conclusion: In our study large number of  Gastro intestinal stromal tumor were present in the stomach. Most common age group was 51-60 years. Majority of  them  were of pure spindle cell morphology. Molecular studies and larger numbers of cases are required for meaningful conclusion to be drawn.

Keywords

  • GIST
  • immunohistochemistry
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European Journal of Molecular & Clinical Medicine
Volume 9, Issue 7
September 2022
Page 3761-3767
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  • Article View: 49
  • PDF Download: 69

APA

Karansinh F. Vala, M. K. P. V. A. R. M. J. R. G. (2022). Histopathological Study of Gastrointestinal Stromal Tumors. European Journal of Molecular & Clinical Medicine, 9(7), 3761-3767.

MLA

Maulik kumar P. Vora, Abhishek Raval, Manan Jadav, Ritesh Gohil, Karansinh F. Vala. "Histopathological Study of Gastrointestinal Stromal Tumors". European Journal of Molecular & Clinical Medicine, 9, 7, 2022, 3761-3767.

HARVARD

Karansinh F. Vala, M. K. P. V. A. R. M. J. R. G. (2022). 'Histopathological Study of Gastrointestinal Stromal Tumors', European Journal of Molecular & Clinical Medicine, 9(7), pp. 3761-3767.

VANCOUVER

Karansinh F. Vala, M. K. P. V. A. R. M. J. R. G. Histopathological Study of Gastrointestinal Stromal Tumors. European Journal of Molecular & Clinical Medicine, 2022; 9(7): 3761-3767.

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