Histopathological Study of Gastrointestinal Stromal Tumors
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 7, Pages 3761-3767
Abstract
Background: Gatrointestinal stromal tumor (GIST), now the most common mesenchymal tumor of the gastrointestinal tract(GIT), has been frequently studied.Objectives: Our aim was to study histopathology, demographic profile, histopathological grading, IHC property and behavior of Gastro intestinal stromal tumor(GIST)
Material & Methods: Retrospectively 50 cases were selected& studied from the department of histopathology of tertiary care hospital, Ahmedabad, India during june 2010 to june 2013
Results: 50 cases were studied in our study. Most common site was stomach(40%)followed by jejunum(18%), rectum(16%)& ileum(12%). Most common age group was 51-60 years. Most common presenting symptoms was abdominal pain (70%) Seventy percent of Gastrointestinal stromal tumor were positive for CD 117(KIT). Histologically majority of them had a pure spindle cell morphology. Eight patients (21%) had recurrent /residual mass of presentation.
Conclusion: In our study large number of Gastro intestinal stromal tumor were present in the stomach. Most common age group was 51-60 years. Majority of them were of pure spindle cell morphology. Molecular studies and larger numbers of cases are required for meaningful conclusion to be drawn.
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