Significance of LADi (Indexed Left Atrial Diameter) as a predictive marker for acute ischemic stroke
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 7, Pages 4079-4085
Abstract
Aims: The present study was designed to assess LAD and LADi as a predictive marker for Acute Ischemic Stroke and to analyse their association in patients with AF in Acute Ischemic Stroke patients.Materials & methods: This study was conducted on 50 patients with acute ischemic stroke and 50 patients without stroke who attended outdoor department or who were admitted in Medicine Department of Guru Nanak Dev Hospital, attached to Government Medical College, Amritsar. The patients were divided into two groups (Group A and B) as follows: Group A includes 50 Patients with acute ischemic stroke, and Group B includes Age and sex matched 50 patients without stroke. Left atrial diameter (LAD) was measured using Two-dimensional echocardiography from the posterior aortic wall to the posterior left atrial wall according to a leading edge to leading edge convention in the parasternal long-axis view at the end-ventricular systole (i.e., just before the mitral valve opening). Indexed left atrial diameter (LADi) was calculated by dividing Left atrial diameter with body surface area (BSA). The data was collected systematically and analysed using Microsoft excel sheet and statistical package for social science version 21.0 (SPSS, Chicago, IL, USA).
Results:In group A, the mean left atrial diameter was 4.02 cm and in group B, the mean left atrial diameter was 3.44 cm. The mean LADi was 2.30 cm/m2 and 1.98 cm/m2 in Group A and Group B respectively. The mean LADi was higher in group A as compared to Group B and the difference was significant statistically (p<0.0001). In addition, among 23 ischemic stroke patients who were having AF, 21.7% had normal LAD and 78.3% had increased LAD. Among 27 control patients who did not have AF, 63% had normal LAD and 37% had increased LAD. The difference was statistically significant (p=0.03). In group A patients in whom AF was absent, 48.1% had normal LADi and 51.9% had increased LADi. In group B patients in whom AF was absent, 84.6% had normal LADi and 15.4% had increased LADi. The difference was again statistically significant (p=0.002)
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