European Journal of Molecular & Clinical Medicine

Abstract

In General Anesthesia, airway management and patient safety are the most important aspects of the patient management.(1,2) Laryngoscopy and tracheal intubation lead to number of physiologic catecholamine releasing responses like hypertension, tachycardia, rise in Intracranial pressure and rise in Intraocular pressure due to sympathetic stimulation. The cardiovascular responses can have serious consequences like Myocardial Ischemia and cardiac arrest.(3) The usual pressor response due to laryngoscopy and intubation is much more exaggerated in hypertensive patients which leads to an increase in myocardial oxygen demand predisposing the already compromised myocardium to myocardial ischemia, infarction and arrhythmias.(4) An ideal induction agent for general anesthesia should have haemodynamic stability, minimal respiratory side effects and rapid clearance.