Abstract

Background: Chronic kidney disease (CKD) is characterized by progressive decline in glomerular filtration rate (GFR). The present study was conducted to assess prescribing patterns of medicines in chronic kidney disease (CKD) patients.
Materials & Methods: 78 patients of CKD of both genders were assessed for clinical profile, drug usage patterns, and medication-related problem. Suspected adverse drug reactions (ADRs) were recorded.
Results: Out of 78 patients, males were 30 and females were 48. Cardiovascular drugs used by patients was diuretics in 24, ACE inhibitors in 10, calcium channel blocker in 8, beta blockerin 6, gastrointestinal drugs such as H2 blockers in 12, proton pump inhibitor in 4, Hematopoietics such as iron in 2, folate in 3 and erythropoietinin 4, antibiotics such as cefoperazone          in 2, levofloxacin in 1 and ceftriaxone in 2 patients. The difference was significant (P<0.05). Adverse drug reactions observed were hyponatremia in 25%, hypokalaemia in 14% and hypoglycaemia in 8% patients. The difference was significant (P< 0.05).
Conclusion: Common administered drugs in patients with chronic kidney disease was cardiovascular drugs followed by gastrointestinal drugs, hematopoietics and antibiotics. Common adverse drug reactions observed were hyponatremia, hypokalaemia and hypoglycaemia.