Clinico-Pathological Profile of Inflammatory Bowel Disease in Tertiary care Hospital
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 7, Pages 4717-4728
AbstractBackground: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease, is increasingly being reported from India and other Asian countries. Both forms of IBD are associated with prominent extra-intestinal manifestations and an increased incidence of gastrointestinal cancer; in addition, both begin relatively early in life and persist for long periods, leading to decreased quality of life indices and a greater than two fold increase in mortality rate.
Methods: The present study was Hospital based study and was done in the Department of Pathology, Government Medical College, Srinagar to analyse the Clinical and Histopathological Profile of patients with Inflammatory Bowel Disease in Tertiary Care Hospital. This was a two year study extending from Ist Oct 2019 to 30 September 2021.The study included biopsies and resected specimen received from Department of Medical Gastroenterology and General Surgery of GMC Srinagar.
Result: During the two year study period in the Department of Pathology Government Medical College Srinagarfrom 1st October 2019 to 30th September 2021. Total of 98 cases were studied during the study period out of which majority of the cases 33(33.6%) were in the age group of 31-45. The age ranged from 1 to 80 years ,53 (54.08%) were male and 45 (45.9%) were female with male is to female ratio of 1.2:1.In our study psychosocial stress was present in 65 patients while as it was absent in 33 cases and this difference was statistically significant. History of junk food and fast food consumption was present in most of IBD patients however in our study no significant association was found between dietary habits and incidence of inflammatory bowel disease. Cryptitis, crypt abscess and mucodepletion were the most commonest findings in our study.
Conclusion: A total of 98 patients were studied in the study period.Psychosocial stress and dietary habits were found to have correlation with occurrence of disease. Thus life style modification with improvement in dietary habits including increased intake of dietary fibres, alleviation of psychosocial stress would possibly help in prevention of this group of diseases.
- Article View: 6
- PDF Download: 31