HRSG Evaluation of Thyroid Nodules with Pathologic Correlation-A Prospective Study
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 7, Pages 4735-4742
Abstract
Introduction: Thyroid nodules are very common and can occur in up to 50% of the adult population. Thyroid nodules can be single or multinodular and benign or malignant. Ultrasonography is often the initial investigative modality used in the detection and characterization of various thyroid nodules.Aim: To evaluate the diagnostic accuracy of HRSG in characterizing benign and malignant thyroid nodules by correlating the sonographic findings with pathological diagnosis as reference.
Material and methods: in this prospective study 40thyroid nodules detected on HRSG were further evaluated with FNAC and/or Histopathological Examination (HPE). The sonographic features such as internal composition, echotexture, shape, margins, presence or absence of peripheral halo, calcification and internal vascularity were correlated with the final diagnosis.
Results: the incidence of malignancy in this study was 15% (6/40). Malignant nodules tended to show solid or predominantly solid composition, hypoechoic pattern, taller than wider shape, irregular margins, micro or punctate calcifications, absence of peripheral halo and internal vascularity. 9cases with suspicion of malignant thyroid nodules demonstrated these 2 or more HRSG features, out of which 6 cases confirmed malignant by pathologic correlation (FNAC/HPE).
Conclusions: HRSG is a sensitive and specific modality in the assessment of thyroid nodules with good overall accuracy. The most useful sonographic features that helped to predict malignancy were a solid composition, hypo echogenicity, taller than wider shape, irregular margins, internal vascularity and presence of micro or punctate calcifications. Thyroid nodules were found to have more malignant potential when 2 or more of these HRSG features were present.
Keywords:
- Article View: 4
- PDF Download: 24