• Register
  • Login

European Journal of Molecular & Clinical Medicine

  1. Home
  2. ASSESSMENT OF EOSINOPHILS AND MAST CELLS IN LEUKOPLAKIA PATIENTS USING SPECIAL STAINS

Current Issue

By Issue

By Author

By Subject

Author Index

Keyword Index

About Journal

Aims and Scope

Editorial Board

Publication Ethics

Indexing and Abstracting

Related Links

FAQ

Peer Review Process

Journal Metrics

News

ASSESSMENT OF EOSINOPHILS AND MAST CELLS IN LEUKOPLAKIA PATIENTS USING SPECIAL STAINS

    Author

    • Arushi Rastogi, Neelampari Parikh, Vaidehi Patel, Stuti Bajaj, Nileshwariba Jadeja, Ruchik Anerao
,

Document Type : Research Article

  • Article Information
  • Download
  • Export Citation
  • Statistics
  • Share

Abstract

Introduction: OPMDs are oral mucosal lesions with an increased peril for malignant transformation, most common being leukoplakia. The chief inflammatory cells accounting for transferring host response to malignancy includes macrophages, plasma cells, neutrophils, eosinophils and mast cells. Both eosinophils and mast cells modulate their function by the release of certain proinflammatory mediators. These bidirectional interactions between the mast cell and eosinophil cell might play an imperative part in the pathogenesis and progression of disorders. Intention of the research was to qualitatively and quantitatively evaluate eosinophil cells and mast cells in leukoplakia cases and control cases histochemically using congo red stain and toluidine blue stain respectively.
Materials and Methods: Study included 30 leukoplakia and 10 normal buccal mucosa cases. Each section was stained with H & E stain, 1% Toluidine Blue stain and 1% Congo Red stain. Both the cells were counted in leukoplakia and normal cases. Cells were also counted in two zones: subepithelial and deeper zone. Mast cells were additionally assessed as intact and degranulated. Statistical analysis was done using‘t’ test and one way ANOVA.
Results: Both eosinophils and mast cells were predominantly found in leukoplakia cases. Mast cells were predominant in deeper zone whereas eosinophils were predominant in subepithelial zone.
Conclusion: Increased number of mast cell and eosinophil count is the prognostic indicator in the progressive invasiveness of leukoplakia to malignancy

Keywords

  • Toluidine Blue
  • Congo Red
  • Mast cells
  • Eosinophils
  • XML
  • PDF 468.73 K
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
    • Article View: 27
    • PDF Download: 47
European Journal of Molecular & Clinical Medicine
Volume 9, Issue 7
September 2022
Page 4974-4983
Files
  • XML
  • PDF 468.73 K
Share
Export Citation
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
Statistics
  • Article View: 27
  • PDF Download: 47

APA

Ruchik Anerao, A. R. N. P. V. P. S. B. . N. J. (2022). ASSESSMENT OF EOSINOPHILS AND MAST CELLS IN LEUKOPLAKIA PATIENTS USING SPECIAL STAINS. European Journal of Molecular & Clinical Medicine, 9(7), 4974-4983.

MLA

Arushi Rastogi, Neelampari Parikh, Vaidehi Patel, Stuti Bajaj, Nileshwariba Jadeja, Ruchik Anerao. "ASSESSMENT OF EOSINOPHILS AND MAST CELLS IN LEUKOPLAKIA PATIENTS USING SPECIAL STAINS". European Journal of Molecular & Clinical Medicine, 9, 7, 2022, 4974-4983.

HARVARD

Ruchik Anerao, A. R. N. P. V. P. S. B. . N. J. (2022). 'ASSESSMENT OF EOSINOPHILS AND MAST CELLS IN LEUKOPLAKIA PATIENTS USING SPECIAL STAINS', European Journal of Molecular & Clinical Medicine, 9(7), pp. 4974-4983.

VANCOUVER

Ruchik Anerao, A. R. N. P. V. P. S. B. . N. J. ASSESSMENT OF EOSINOPHILS AND MAST CELLS IN LEUKOPLAKIA PATIENTS USING SPECIAL STAINS. European Journal of Molecular & Clinical Medicine, 2022; 9(7): 4974-4983.

  • Home
  • About Journal
  • Editorial Board
  • Submit Manuscript
  • Contact Us
  • Glossary
  • Sitemap

News

 

For Special Issue Proposal : editor.ejmcm21@gmail.com

Newsletter Subscription

Subscribe to the journal newsletter and receive the latest news and updates

© Journal Management System. Powered by ejournalplus