European Journal of Molecular & Clinical Medicine

Abstract

AIM: To assess if cerebrouterine ratio would be complementary to cerebroplacental ratio in predicting adverse neonatal outcome in preeclamptic pregnant women
MATERIALS AND METHODS: This research was conducted at the Department of  Obstetrics and Gynecology, with clearance from the institute's ethical committee. 100 pre eclamptic pregnant women between 34 to 37 weeks of gestation were included in the study. Cerebroplacental ratio(CP) and cerebrouterine(CU) ratio via latest Doppler USG before delivery was calculated. Patients were followed up till delivery and perinatal outcome was analyzed.
RESULTS: Abnormal CU ratio was seen in 45 cases and CP ratio was seen in 40 cases CU ratio showed statistical significance for preterm births (p=0.002), fetal hypoxia (0.02),NICU admission (p=0.006) .CP ratio showed statistical significance for preterm births (p<0.001), low APGAR (0.015),adverse perinatal outcome (p=0.05)
Sensitivity for pre term of CU ratio was 71.1% and CP ratio was 72%, for fetal hypoxia sensitivity of CU ratio was 20% and CP ratio was 10%, for low APGAR sensitivity of CU ratio was 77.7% and CP ratio was 77.5%, for low birth weight sensitivity of CU ratio was 60% and CP ratio was 65%, for NICU admission sensitivity of CU ratio was 88.8% and CP ratio was 65% and for adverse perinatal outcome (IUD) sensitivity of CU ratio was 57.7% and CP ratio was 60%.
CONCLUSION: Diagnostic accuracy of CP ratio was almost similar (78%) as compared to CU ratio (75%) in diagnosing the perinatal outcome and was only better than 3%. However, the combined Doppler results were more sensitive to abnormal outcome.