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Assessment of correlation of various prostate pathologies with serum prostate specific antigen

    Author

    • Dr. Abhijeet Katkar, Dr. Yogesh Jadhav, Dr. Anil Huddedar, Dr. Sachin Misal, Dr. Prasad Hake
,

Document Type : Research Article

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Abstract

Background: There are various prostate pathologies. Among all, Benign Prostatic Hyperplasia (BPH) is a common health issue among ageing men globally. The present study was conducted to assess correlation of various prostate pathologies with serum prostate specific antigen.
Materials & Methods: 58 male patients with various prostate pathologies presenting with LUTS underwent DRE and were worked up with USG KUBP, Serum PSA and biopsy. A trans-abdominal ultrasound examination was done to assess the size of the prostate gland. Patients with suspicious DRE finding or increased Serum PSA levels (defined as more than 4 ng/ml) underwent prostate biopsy
Results: Age group 50-60 years had PSA level 3.5 ng/ml, 61-70 years had 15.4 ng/ml and 71-80 years had 11.9 ng/ml. The difference was significant (P< 0.05). IPSS was mild in 29, moderate in 23 and severe in 6 patients. PSA (ng/ml) level in mild patients was 4.7, in moderate was 6.2 and in severe was 13.7. PSA (ng/ml) level in prostate grade I patients was 4.16, in grade II was 12.3 and in grade III was 31.5 and in grade IV was 42.6. The difference was significant (P< 0.05).
Conclusion: The mean serum PSA levels rises with increasing age. Serum PSA levels has a significant correlation with international prostate symptom severity scoring wherein mean serum PSA level rises with severity of LUTS. Prostate-specific antigen is specific for prostatic tissue and is raised in both benign and malignant lesions of prostate.

Keywords

  • Benign Prostatic Hyperplasia
  • Prostate Specific Antigen
  • Men
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European Journal of Molecular & Clinical Medicine
Volume 9, Issue 7
September 2022
Page 5478-5482
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  • Article View: 13
  • PDF Download: 31

APA

Dr. Prasad Hake, D. A. K. D. Y. J. D. A. H. D. S. M. (2022). Assessment of correlation of various prostate pathologies with serum prostate specific antigen. European Journal of Molecular & Clinical Medicine, 9(7), 5478-5482.

MLA

Dr. Abhijeet Katkar, Dr. Yogesh Jadhav, Dr. Anil Huddedar, Dr. Sachin Misal, Dr. Prasad Hake. "Assessment of correlation of various prostate pathologies with serum prostate specific antigen". European Journal of Molecular & Clinical Medicine, 9, 7, 2022, 5478-5482.

HARVARD

Dr. Prasad Hake, D. A. K. D. Y. J. D. A. H. D. S. M. (2022). 'Assessment of correlation of various prostate pathologies with serum prostate specific antigen', European Journal of Molecular & Clinical Medicine, 9(7), pp. 5478-5482.

VANCOUVER

Dr. Prasad Hake, D. A. K. D. Y. J. D. A. H. D. S. M. Assessment of correlation of various prostate pathologies with serum prostate specific antigen. European Journal of Molecular & Clinical Medicine, 2022; 9(7): 5478-5482.

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