European Journal of Molecular & Clinical Medicine

Abstract

Background: Primary care doctors are in a good position to help men at risk for osteoporosis-related fractures get treated early. However, effective screening methods are needed. The goal of this study was to prove that the Male Osteoporosis Risk Estimation Score (MORES) is a good way to find men who are more likely to have osteoporosis.
Materials and Methods: This was a blinded analysis of the MORES, which was given to men over 60 years old in a cross-sectional sample. During an outpatient visit, the participants filled out a research questionnaire and had a dual-energy X-ray absorptiometry (DXA) scan to measure their bone density. The MORES was tested to find out its sensitivity, specificity, and area under the curve (AUC). The number needed to screen (NNS) to prevent one more major osteoporotic fracture was used to measure effectiveness.
Results: A total of 70 men completed the study. The mean age was 70.2 ± 6.9 years; 76% were non-Hispanic white. Fifteen men (4.3%) had osteoporosis of the hip. The operating characteristics were sensitivity 0.80 (95% confidence interval [CI], 0.52–0.96); specificity 0.70 (95% CI, 0.64–0.74), and AUC of 0.82 (95% CI, 0.71–0.92). Screening with the MORES yielded a NNS to prevent one additional major osteoporotic fracture over 10 years with 259 (95% CI, 192–449) compared to 636 for universal screening with a DXA.
Conclusion: This study proved that the MORES is a good and quick way to find men who are more likely to get osteoporosis and could benefit from a diagnostic DXA scan