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  2. Volume 9, Issue 7
  3. Author

Online ISSN: 2515-8260

Volume9, Issue7

HEPATOCELLULAR CARCINOMA WITH NEUROENDOCRINE DIFFERENTIATION PRESENTING AS METASTATIC SOFT TISSUE LESION.

    Dr. Vinayak Kshirsagar Dr. Mahendra Bendre Dr. Rishi Chowdhary Narra

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 5909-5913

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Abstract

Hepatocellular carcinoma is a common subtype of primary liver malignancy, in addition to cells with hepatic differentiation. It can rarely contain additional cell populations such as neuroendocrine carcinoma (NEC) or cholangiocarcinoma. Mixed hepatocellular carcinoma – neuroendocrine carcinoma (HCC-NEC) are extremely rare tumours, constituting about 0.40% of all primary hepatic malignancies. Most of them are incidentally diagnosed after surgical resection of liver and have a very aggressive behaviour. Very few cases have been reported worldwide.
We hereby present a unique case of HCC–NEC in an elderly male, the patient presenting to us as a soft tissue mass in paraspinal region which revealed a metastatic lesion from a primary hepatic HCC–NEC tumour, only after undergoing investigations. Ours is probably the first case in literature where a primary HCC-NEC has presented as a metastatic soft tissue deposit. Inspite of multimodalities of treatment like surgical resection and chemotherapy, the prognosis in such cases remains extremely poor.
Keywords:
    Hepatocellular carcinoma neuroendocrine differentiation paravertebral soft tissue tumour metastatic lesion
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(2022). HEPATOCELLULAR CARCINOMA WITH NEUROENDOCRINE DIFFERENTIATION PRESENTING AS METASTATIC SOFT TISSUE LESION.. European Journal of Molecular & Clinical Medicine, 9(7), 5909-5913.
Dr. Vinayak Kshirsagar Dr. Mahendra Bendre Dr. Rishi Chowdhary Narra. "HEPATOCELLULAR CARCINOMA WITH NEUROENDOCRINE DIFFERENTIATION PRESENTING AS METASTATIC SOFT TISSUE LESION.". European Journal of Molecular & Clinical Medicine, 9, 7, 2022, 5909-5913.
(2022). 'HEPATOCELLULAR CARCINOMA WITH NEUROENDOCRINE DIFFERENTIATION PRESENTING AS METASTATIC SOFT TISSUE LESION.', European Journal of Molecular & Clinical Medicine, 9(7), pp. 5909-5913.
HEPATOCELLULAR CARCINOMA WITH NEUROENDOCRINE DIFFERENTIATION PRESENTING AS METASTATIC SOFT TISSUE LESION.. European Journal of Molecular & Clinical Medicine, 2022; 9(7): 5909-5913.
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