European Journal of Molecular & Clinical Medicine

Abstract

Background: Cervical cancer, mainly caused by HPV infection is the leading cancer in Indian women and the second most common cancer in women worldwide, accounting for approx 288,000 deaths annually.
Objectives: The objective of this study is to assess the various hematological parameters and anemia profile in cervical cancer patients.
Methodology: This case control study consist of 150 patients of cervical   cancer along with 150 healthy subjects of précised matched age within the institution. EDTA and plain blood samples were collected from all participants and were analysed for Hemoglobin(hb) and anemia profile parameters like S..iron, S.Ferritin, S.Total  iron binding capacity(TIBC). and s.vitamin B12. Results obtained were analyzed statistically to see the significance of differences.
Results: The Mean concentration of haemoglobin in case group was  10.41 ±1.154 while that of  control group 12.25 ±1.12 and the difference among them found to be  highly significant .The Mean concentration of S.iron was  in case group was 173.28±68.13 and 117.06 ±36.01 in case and control group respectively and the difference among them found to be  highly significant. similar to that  S.TIBC concentration in case group was 182.5 ±60.56 and in control group 271.73 ±51.63. Serum ferritin concentration in case group was 160.13 ±89.67 while that of control group 170.03 ±71.71 and p value is 0.2918 so the difference among them is not significant while the level of S. Vitamin B12 was  499.97 ±284.4 and 352.18 ±169.22 in case and control group respectively and the difference among them found to be  highly significant.