In vitro evaluation of the anti-cancer efficacy of Tecoma stans hydroethanolic leaf extract against a liver cancer cell line (HepG2).
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 8, Pages 628-637
AbstractFlavonoids, alkaloids, quinones, tannins, and traces of saponins and amino acids were found in Tecoma stans. The presence of phytochemicals has been recorded in almost all sections of the plant (leaves, root, flower, seed, fruit, bark) and hence the plant's usage in medical domains. Cancer, along with cardiovascular illnesses, is one of the main causes of death worldwide. The goal of this study is to see if tecoma stans hydro ethanolic leaf extract has anti-cancer properties against liver cancer.
Human liver cancer cell line (HepG2 ) was brought from NCCS, Pune, India. Cell viability test and Gene expression analysis were carried out for Wnt and beta catenin mRNA Gene expression using MTT and PCR respectively. The results were analyzed using appropriate statistical tools
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