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  1. Home
  2. Volume 9, Issue 8
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Online ISSN: 2515-8260

Volume9, Issue8

In Silico Analysis To Identify The Inhibitory Potential Of Endogenous Superoxide Dismutase On Apoptotic Markers Relevant To Breast Cancer.

    Gopika. G.G Lavanya Prathap Selvaraj Jayaraman Preetha. S

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 638-648

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Abstract

Breast cancer arises when certain breast cells start to grow abnormally they  divide and replicate at a greater rate than normal cells. Regular exercise helps to reduce breast cancer by 10 to 20 percent. AIM: To analyse the inhibitory potential of endogenous over expression of superoxide dismutase (SOD) on apoptotic markers in breast cancer through silico analysis.
    The molecular docking analysis is a bioinformatic study. The endogenous substance SOD which is secreted after exercise is used as a target protein. The interaction of SOD with proteins relevant to breast cancer namely Bcl-2, Bcl-xl, Bax are included for docking analysis. The protein structure is retrieved using protein data bank, protein protein docking done using patch dock server followed by visualisation of protein -protein interaction using pymol.
Keywords:
    Breast Cancer superoxide dismutase apoptotic markers,’ exercise’ bcl-2 bcl xl bax proteins Innovative
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(2022). In Silico Analysis To Identify The Inhibitory Potential Of Endogenous Superoxide Dismutase On Apoptotic Markers Relevant To Breast Cancer.. European Journal of Molecular & Clinical Medicine, 9(8), 638-648.
Gopika. G.G; Lavanya Prathap; Selvaraj Jayaraman; Preetha. S. "In Silico Analysis To Identify The Inhibitory Potential Of Endogenous Superoxide Dismutase On Apoptotic Markers Relevant To Breast Cancer.". European Journal of Molecular & Clinical Medicine, 9, 8, 2022, 638-648.
(2022). 'In Silico Analysis To Identify The Inhibitory Potential Of Endogenous Superoxide Dismutase On Apoptotic Markers Relevant To Breast Cancer.', European Journal of Molecular & Clinical Medicine, 9(8), pp. 638-648.
In Silico Analysis To Identify The Inhibitory Potential Of Endogenous Superoxide Dismutase On Apoptotic Markers Relevant To Breast Cancer.. European Journal of Molecular & Clinical Medicine, 2022; 9(8): 638-648.
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