European Journal of Molecular & Clinical Medicine

Abstract

Introduction: There is a wide spectrum of salivary gland lesions with morphological and clinical diversity which is a difficult task for histopathological interpretation. There are three major salivary glands-parotid, submandibular, and sublingual as well as minor salivary glands distributed throughout the mucosa of the oral cavity. Neoplastic and non-neoplastic disease may develop within any of these.
Aims: (1) To study the histopathological features of salivary gland lesions, (2) To study the prevalence of salivary gland lesions in tertiary care hospital, (3) To evaluate the incidence, age at the occurrence, and sex ratio among the patients with salivary gland lesions, (4) To compare the result of our study with other studies.
Material and Method: It was a retrospective study of 29 cases of salivary gland tumors, diagnosed on histopathological examination over a period of 5 years (January 2017 to December 2021) in the Department of Pathology, GMERS Medical college & Hospital, Valsad. Histopathological examination was done on formalin fixed, paraffin embedded tissue sections stained with hematoxylin and eosin.
Result: In present study, out of 29 cases, 24 cases (82.76%) were benign and 05 cases (17.24%) were malignant. Most common benign tumor of salivary gland was pleomorphic adenoma followed by Basal Cell adenoma. Most common malignant tumor of salivary gland was mucoepidermoid carcinoma.
Conclusion: Histopathological study of salivary gland lesions is the most important method in establishing the final diagnosis and subtyping. Salivary gland tumors are relatively less common and they exhibit a wide variety of microscopic appearances even within one particular lesions.