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  2. Volume 9, Issue 7
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Online ISSN: 2515-8260

Volume9, Issue7

A comparative study of intranasal steroids with intranasal antihistamines sprays v/s intranasal steroids sprays alone in management of allergic rhinitis

    Somasundaram Subramaniam, Praveenkumar Jayaraj, Parameshwaran Arumugam

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 7089-7094

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Abstract

Background: Allergic rhinitis is a chronic upper airway disease of increasing prevalence and remains an important healthcare problem. Present study was aimed to compare intranasal steroids with intranasal antihistamines sprays v/s intranasal steroids sprays alone in management of allergic rhinitis. Material and Methods: Present study was comparative, prospective & non-randomized study, conducted patients from 18-45 years of age group, either gender, attending the ENT outpatient clinic, clinically diagnosed with allergic rhinitis. 60 patients by computer generated chits randomly allocated to group S (intranasal steroids) & group SA (intranasal steroids & intranasal antihistamines). Nasal Obstruction Symptom Evaluation (NOSE) score was calculated at baseline & after 6 weeks. Results: 60 patients were randomly divided in group S (n=30) & group SA (n=30). Both groups had comparable distribution of patients according to age & gender. Baseline NOSE score (Group S - 82.17 ± 10.52 & Group SA - 83.75 ± 11.94) were comparable & difference was not significant statistically (p - 0.078). At 6 weeks a significant fall in Absolute eosinophil count was noted in groups S (82.17 ± 10.52 vs 49.28 ± 7.56) as well as group SA (83.75 ± 11.94 vs 22.2 ± 6.97) & difference was statistically significant (p<0.001). At 6 weeks, less NOSE score was noted in group SA (22.2 ± 6.97) as compared to group S (49.28 ± 7.56) & difference was statistically significant (p - 0.021). Conclusion: Combination of intranasal steroids with intranasal antihistamines sprays has significant reduction of symptoms in allergic rhinitis patients when compared to intranasal steroids spray alone.
Keywords:
    Allergic rhinitis intranasal steroids intranasal antihistamines NOSE score
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(2022). A comparative study of intranasal steroids with intranasal antihistamines sprays v/s intranasal steroids sprays alone in management of allergic rhinitis. European Journal of Molecular & Clinical Medicine, 9(7), 7089-7094.
Somasundaram Subramaniam, Praveenkumar Jayaraj, Parameshwaran Arumugam. "A comparative study of intranasal steroids with intranasal antihistamines sprays v/s intranasal steroids sprays alone in management of allergic rhinitis". European Journal of Molecular & Clinical Medicine, 9, 7, 2022, 7089-7094.
(2022). 'A comparative study of intranasal steroids with intranasal antihistamines sprays v/s intranasal steroids sprays alone in management of allergic rhinitis', European Journal of Molecular & Clinical Medicine, 9(7), pp. 7089-7094.
A comparative study of intranasal steroids with intranasal antihistamines sprays v/s intranasal steroids sprays alone in management of allergic rhinitis. European Journal of Molecular & Clinical Medicine, 2022; 9(7): 7089-7094.
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