European Journal of Molecular & Clinical Medicine

Abstract

Some bacteria become resistant to many different antibioticsare called as multidrugresistant. Multidrug-resistant bacteria isdifficult to treat andspread the antibiotic resistance gene. Methicillin, as the first beta-lactamase resistant penicillin, was used to treat Staphylococcusaureus infection in 1961. The first methicillin-resistant S. aureus (MRSA) was identified in the United Kingdom in the same year. It appeared in the United States in 1981 among intravenous drug users. Methicillin-resistant Staphylococcus aureus (MRSA) is an important agent of hospital-acquired infection.