European Journal of Molecular & Clinical Medicine

Abstract

Gastric xanthelasma also known as gastric xanthoma is a benign asymptomatic condition that can mimic malignancy and is associated with a few other conditions of the stomach. A careful examination of the gastrointestinal tract for other co-existing conditions and histopathological confirmation of the diagnosis is needed. Gastric xanthomas are comparatively rare their incidence ranges from 0.018-0.8%, which is more frequent when compared to esophageal and duodenal xanthomas. The most common location of xanthelasmas of the gastrointestinal tract was the stomach (76%), followed by the esophagus (12%) and duodenum (12%). Here we report two patients who presented with symptoms of dyspepsia for 2 months and 3 months respectively. An endoscopy was done to find the cause of dyspepsia. Histopathological diagnosis of gastric xanthelasma was made for both patients. Gastric xanthelasma is now viewed as a warning sign of the presence of gastric malignancy. Here we report these 2 cases to emphasize that gastric xanthoma should not be overlooked when encountered endoscopically and histopathological examination is essential for diagnosis.