European Journal of Molecular & Clinical Medicine

Abstract

Background: Diabetes mellitus (DM) is a heterogenous group of metabolic disorders with chronic hyperglycemia and glucose intolerance. Satisfactory glycemic and weight control in outpatient diabetic subjects is important. Present study was aimed to study association of BMI with glycemic control in type 2 diabetes mellitus patients at a tertiary hospital.
Material and Methods: Present study was hospital based, cross-sectional study, conducted in subjects (males and females between 26–45 years) attending outpatient department of Medicine, known diabetic patients, underwent BMI calculation and HBa1c estimation.
Results: In present study, total 150 subjects studied, 50 each from group A, B, C (depending on duration of diabetes), in each group 25 male & 25 female. Subjects were divided according to BMI values & compared with gender. There was no significant difference found in male & females according BMI distribution (p – 0.72). According to BMI majority were overweight (72 cases) followed by normal BMI (54 cases) & obese (24 cases). We noticed, HBA1C ≥ 8 commonly in overweight & obese subjects than normal BMI subjects, difference was statistically significant (p<0.01). Descriptive statistics calculated using Pearsons correlation. R values were 0.034, 0.242 & -0.022 for A,B,C groups respectively, which was significant in obese group. When we compared BMI and glycated Hb values within the three groups, a significant correlation was noted between BMI and glycated Hb values.
Conclusion: As BMI value rises, so does the HbA1c level. Majority of diabetic subjects with a BMI > 30 (obese group) had HbA1c levels greater than 8%. Statistical analysis reveals a substantial positive connection between BMI and HbA1c (p value 0.001).