A Hospital-Based Study To Assess The Predictive Value Of Preoperative Complete Blood Count Components On The Occurrence Of Surgical Site Infection After Surgery
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 8, Pages 1884-1891
Aim: The aim of this study was to examine whether a set of routine preoperative blood tests including WBCC, CRP, Creatinine (eGFR), albumin and hemoglobin predict the risk of SSI either alone or in combination.
Methods: The observational cohort study was designed to evaluate the optimal timing of surgical antimicrobial prophylaxis. The preoperative blood test parameters hemoglobin, creatinine, albumin, CRP and white blood cell count were collected in those patients considered to have an indication for preoperative blood testing as per clinical standards. A total of 200 patients were included in the analysis for the RCT and hence assessed for the availability of preoperative levels of the blood parameters of interest.
Results: A complete set of preoperative WBCC, CRP, albumin, creatinine and hemoglobin measurements was present for 48 of 100 patients (48%). The 100 patients with preoperative blood tests available were older, had higher ASA scores, had more secondary diagnoses, were more likely to be women. The 30-day SSI rate was higher in patients with preoperative blood work than in the group without (5.8% vs. 4.5%, p=0.044).
Conclusion: This study demonstrates strong associations between the levels of routine preoperative blood parameters and the risk of SSI. However, none of the blood parameters examined in this study showed striking predictive abilities in terms of surgical site infections and hence, the decision to postpone procedures to optimize patient factors that impact preoperative blood results cannot be generally recommended at a defined cut off.
- Article View: 3
- PDF Download: 26