Abstract

Inhospitalspyogenicinfectionisoneofthemajorcauseofmorbidity.Increasingmultidrugresistant strains has made treatment of such infection difficult. For correct antibiotic use, everypus samplesshouldundergocultureandsensitivity.
Aim:Toisolatebacteriafrompussamplesandantibioticsensitivitypatterninvariouspusisolates.
Objectives:
i) To study the distribution pattern and prevelance of bacteria causing pyogenic infection.
ii) TostudyAntibioticSensitivityPatternoforganism isolatedfrompus.
Methods: The study was conducted in the Department of Microbiology, T.S. MisraMedical College & Hospital, Lucknow, for a duration of 6 months. 256 pus samples fromvarious wards with suspected pyogenic infection were studied. Bacteria were isolated,identified and antibiotic profile was determined from pus samples using standard protocol.
Results: In our study, out of 256 pus samples studied, 159 (62.10%) samples werepositiveforgrowth. Grampositivebacteriaoutnumberedgramnegativeisolates.CommonestisolatewasStaphylococcusaureus,followedbyCoagulaseNegativeStaphylococcusand Pseudomonasaeruginosa.AllStaphylococcusaureusweresensitive to Vancomycin and Linezolid. All Pseudomonas aeruginosa were sensitive toColistin. In Enterobacteriaceae group most effective antibiotic were Colistin and Tigecyclin.
Conclusion:Itisimportantforacliniciantosendallthepussamplesformicrobiologicalanalysisandtheirantibiogrambeforeputtingcasesonantibioticsothatemergenceofdrugresistancecanbeminimized.