European Journal of Molecular & Clinical Medicine

Abstract

Objective: To study the value of computed tomography evaluation in early diagnosis of acute pancreatitis and to evaluate the complications of acute pancreatitis using the Modified computed tomography severity index(MCTSI) and its correlation with clinical outcome
Methods: This observational study was conducted at a tertiary health center over the period of 2 years from 2020-2022.The study sample included 100 patients with clinical/laboratory/ultrasonography diagnoses of acute pancreatitis, who were willing to undergo Contrast-enhanced computed tomography & included in the study. These patients based on their MCTSI (Modified CT Severity Index) score were subjected to either conservative management or surgical/endoscopic intervention. An attempt was made to establish a correlation between the MCTSI score at presentation and possible local/systemic complications as well as clinical outcomes.
Results: The peak incidence was in the 4th decade. The mean age group in our study is
53.6 years with a standard deviation of 12.04.Out of 100 patients, 71 were males and 29 were females. Among 100 patients evaluated Clinically, biochemically, and radiologically were found to have complications in 51 patients.95% of patients recovered with a favorable clinical outcome as compared to 5% of patients who succumbed to organ failure secondary to severe acute pancreatitis.The sensitivity and specificity of the MCTSI score in predicting the clinical outcome of acute pancreatitis in this study was 100%.The p-value of MCTSI in predicting clinical outcomes was <0.057 which was statistically significant. The p-value of MCTSI in predicting complications was <0.00001 which was significant indicating a positive correlation.