European Journal of Molecular & Clinical Medicine

Abstract

Background and objectives. Obesity is a major concern in our era with many adolescents and adults being obese.Obese patients with metabolic syndrome are more prone for cardiovascular risk. Obese individuals have numerous physiological changes which predispose them to many dermatological conditions. This is of concern to us as many of these conditions can act as markers for obesity and impending systemic consequences of obesity. This study was done to find the common dermatoses associated in adults with a BMI of > 30 kg/m2 who presented. Methodology All adult patients, of both sexes, who have a BMI > 30.0 and/or waist circumference > 90cm in males and > 80cm in females were included in the study.A detailed history of the patients was taken Morphology of skin lesions, sites of involvement, number of lesions were noted. A complete systemic and dermatological examination was carried out in all patients. ResultsThe age range of patients in this study was 18-85 years and the mean age was 40± 12.50. Acanthosis nigricans and skin tags had a strong correlation with obesityand Metabolicsyndrome. It was noted that in patients with acanthosis nigricans and skin tags, who were found to have metabolic syndrome, had elevated fasting plasma leptin levels but no elevation in fasting plasma Insulin levels.