An audit of the use of blood components in acute systemic infections and its correlation with clinical outcome in children
European Journal of Molecular & Clinical Medicine,
2023, Volume 10, Issue 1, Pages 227-230
AbstractBackground: The present study was an audit for evaluating the use of blood components in acute systemic infections and its correlation with clinical outcome in children.
Materials & methods: A total of 100 subjects were enrolled. Any preterm and term neonates admitted to the NICU and Neonatal Intermediate Care Unit (NIMC) and receiving any transfusion, i.e., fresh frozen plasma (FFP), red cell concentrate (RCC), platelets, and exchange transfusion were included. The data was collected from the medical records. Patients were categorized according to the classification of neonatal conditions by the International Classification of Diseases 11th Revision (ICD-11).
Results:A total of 100 subjects were enrolled. Out of 100 neonates, 70 neonates received fresh frozen plasma. The platelet concentrate was received by 32 individuals whereas whole blood was received by 12 subjects. Transfusion data for all of the components yielded a statistically significant result. A condition chewing blood products are sepsis (82), meningitis (4). The other disorders comprise of 11 patients.
Conclusion: Over the few decades, there has been an increasing focus on use of blood components in managing pediatric patients with acute systemic infections. The exact ontogeny of individual components of the hematological system, and how they interact and drive the response to infectious agents, is of particular importance in understanding paediatric systemic infections. Hence; further studies are recommended
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