European Journal of Molecular & Clinical Medicine

Abstract

Congenital pulmonary airway malformation (CPAM) - previously known as congenital cystic adenomatoid malformation (CCAM) - is a rare developmental malformation of the lower respiratory tract. It is accepted that abnormal airway patterning and branching during lung morphogenesis results in the appearance of lung cysts.¹ It is composed of aberrant lung tissue that keeps expanding and resembles bronchioles physically, but lacks cartilage, alveoli, and bronchial glands. These masses may become overdistended leading to respiratory distress due to air trapping mechanism. Treatment of symptomatic lesion is usually surgical resection of the lesion or affected lobe.