European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Meningiomas are the most prevalent primary non-glial intracranial brain tumours to develop from the meninges, accounting for 15–30% of all primary cerebral tumours. Even though the majority of these tumours are benign, a very few number of them are malignant. Amongst the meningiomas more than 90% are solitary for unfamiliar reasons. Only risk factor known for meningioma are ionizing radiation. The WHO assigns these tumours grades I, II, and III. Surgery can treat benign meningiomas, however higher grade meningiomas need radiation following surgery because of their high recurrence rate and aggressive behaviour. Materials and methods: This case study was conducted retrospectively in the pathology department of a tertiary care hospital in Pune from the year 2020 to 2022. A total of 39 biopsies were received for histopathological examination and some as frozen samples during this period. Results: In our study 29 patients were females (74.35%) and 10 patients were males (25.65%). The age group between 41 and 50 is the most common (28.2%).Meningothelial meningioma was the most frequent histological form, occurring in 23 cases (58.9%), followed by transitional meningioma in 7 patients (17.9%). (17.9%), fibrous meningioma(7.6%). Conclusion: For WHO Grade I tumours and those who have had a complete surgical resection, the prognosis is favourable; however, for grade III tumours, it is less favourable. Because some histological subtypes with higher WHO Grades have a greater risk of recurrence and a worse prognosis, accurate histological grading and typing are necessary