European Journal of Molecular & Clinical Medicine

Abstract

Aims and objectives: The present study was conducted to study red cell distribution width (RDW), and red cell distribution width to platelet ratio (RPR) as early predictors of severity in Acute Pancreatitis and their correlation with BISAP scoring system.
Materials and Methods: A hospital based prospective observational study was conducted in the Department of General Medicine, Mahatma Gandhi Medical College & Hospital, Jaipur. Total 117 Patients diagnosed with Acute Pancreatitis according to Revised Atlanta Criteria were included in the study.
Results: According to regression analysis, red cell distribution width to platelet ratio [RPR] was the only predictor of the severity of pancreatitis as compared to RDW and BISAP score.
Conclusion: From this study we confirmed that red cell distribution width to platelet ratio (RPR) is a good predictor of disease severity in patients with acute pancreatitis.
Keywords: acute pancreatitis, RDW, BISAP score
Introduction
Acute pancreatitis (AP) is an inflammatory disease of the pancreas gland that may cause local and systemic complications. Since the disease may cause severe organ damage and may have some fatal complications, assessment of disease severity is essential to determine their therapeutic strategies.[i]
From Indian population no data is available regarding the actual incidence of the disease. Only some idea of incidence can be obtained from patients admitted in different tertiary care centres in India (in SP medical college Bikaner, Rajasthan 50 cases per year, Indira Gandhi



[i] Joshua A. Greenberg MD, Jonathan Hsu, et al. Clinical practice guideline: management of acute pancreatitis Can J Surg 2016;59:128-140.